A typical Hill plot (log [Y O2 /(1- Y O2 )] vs log P O2 )for hemoglobin-oxygen binding does not yield a straight line as it does for myoglobin. Which of the following is the best explanation for this?
Given the pK a values for phosphoric acid of 2.14, 6.86 and 12.4, what is the ratio of HPO 4 2- /H 2 PO 4 - in a typical muscle cell where the pH is 7.2?
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