Which of the following drugs are not matched correctly with their mode of action?
A) Flucytosine: targets fungal DNA replication by blocking transcription when it is converted to a nucleic acid analog that blocks DNA and RNA synthesis
B) polyenes: directly interacts with ergosterols which causes targeted plasma membranes to become leaky and leads to cell lysis
C) allyamines: inhibits enzymes that build ergosterol which leads to improperly built plasma membranes and fungal cell lysis
D) azoles: inhibits ribosome function by entering ribosome as a tRNA, covalently binding to mRNA, and forcing the destruction of the complex
E) echinocandin drugs: inhibits fungal cell wall synthesis by targeting an enzyme that makes a component of the fungal cell wall
Answer: D
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