If not diagnosed at birth, a newborn with 21-hydroxylase (21-OH) deficiency and salt wasting will develop which of the following problems by days 10 to 14 of life?
a. seizures c. thyroid storm
b. coma d. adrenal crisis
D
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A Incorrect. If not diagnosed at birth, a newborn with 21-hydroxylase (21-OH) deficiency and salt wasting will have lower sodium level, higher potassium level and a lower volume of blood circulation, not subject to seizures.
B Incorrect. If not diagnosed at birth, a newborn with 21-hydroxylase (21-OH) deficiency and salt wasting will have lower sodium level, higher potassium level and a lower volume of blood circulation, with coma as a potential; but, greater risks possible.
C Incorrect. If not diagnosed at birth, a newborn with 21-hydroxylase (21-OH) deficiency and salt wasting will develop a life-threatening hyponatremia, hyperkalemia, and hypovolemia by day 10-14 of life. This is not known as a thyroid storm.
D Correct. If not diagnosed at birth, a newborn with 21-hydroxylase (21-OH) deficiency and salt wasting will develop a life-threatening hyponatremia, hyperkalemia, and hypovolemia by day 10-14 of life. This is known as adrenal crisis.
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