Explain the role of the laboratory professional in stem cell transplantation
What will be an ideal response?
Answer: The role of the laboratory professional is inherent in all phases of testing for stem cell transplant:
Pretransplant testing:
HLA compatibility testing
ABO compatibility testing (if needed)
Absolute neutrophil count (CBC) for chemotherapy dosage
Peritransplant testing:
Apheresis of stem cells
WBC/MNC counts
CD34 enumeration by flow cytometry
Processing and cryopreservation of stem cells
Bacterial, viral, fungal cultures
Cell cultures for enumeration of CFUs
Post-transplant testing:
Short-term engraftment CBC
Long-term engraftment chimerism studies
Investigation of possible complications
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Indicate whether the statement is true or false
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Fill in the blank(s) with the appropriate word(s).