Which drug class, with a negative inotropic effect, is prescribed for the treatment of heart failure?
1. ACE inhibitors
2. Cardiac glycosides
3. Beta-adrenergic blockers
4. Angiotensin-receptor blockers
Correct Answer: 3
Rationale 1: ACE inhibitors have a positive inotropic effect.
Rationale 2: Cardiac glycosides have a positive inotropic effect.
Rationale 3: Beta-adrenergic blockers have a negative inotropic effect.
Rationale 4: Angiotensin-receptor blockers have a positive inotropic effect.
Global Rationale: Beta-adrenergic blockers have a negative inotropic effect. ACE inhibitors have a positive inotropic effect. Cardiac glycosides have a positive inotropic effect. Angiotensin-receptor blockers have a positive inotropic effect.
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