The presence of lead in the central nervous system will cause:
a. bleeding in the ventricles of the brain
b. the release of large amounts of adrenocorticotropic hormone (ACTH) by the anterior pituitary, which leads to systemic dysfunction
c. an increase in membrane permeability causing a fluid shift into brain tissue
d. seizures and the risk for status epilepticus
C
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A Incorrect. Lead causes a fluid shift into the brain tissues, not bleeding in the ventricles.
B Incorrect. Lead in the central nervous system causes serious damage in the brain, some say irreversible damage. The pituitary is not affected.
C Correct. Lead causes an increase in membrane permeability, causing a fluid shift into brain tissue, producing increased intracranial pressure, ischemia, and cellular destruction.
D Incorrect. Seizures may result, but not to be confused with status epilepticus.
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