A client has requested a pregnancy termination using mifepristone (RU-486) and misoprostol (Cytotec). Which statement by the client indicates the need for further instruction about these medications?
1. "I will avoid drinking grapefruit juice while I am taking this medication."
2. "I know that I will probably experience nausea with this medication."
3. "I'll take these medications with me while I am away on vacation."
4. "I will call the clinic if I have excessive bleeding."
Correct Answer: 3
Rationale 1: Clients should avoid grapefruit juice because it decreases the serum levels of mifepristone.
Rationale 2: Most clients experience nausea, dizziness, headache, vomiting, fatigue, abdominal pain, and cramping when taking these medications.
Rationale 3: The client must receive further instruction that taking this medication requires three office visits; therefore, the client will not be able to go on vacation while taking the medications.
Rationale 4: Clients using mifepristone for early pregnancy termination must call the health care provider if excessive bleeding occurs.
Global Rationale: The client must receive further instruction that taking this medication requires three office visits; therefore, the client will not be able to go on vacation while taking the medications. Clients should avoid grapefruit juice because it decreases the serum levels of mifepristone. Most clients experience nausea, dizziness, headache, vomiting, fatigue, abdominal pain, and cramping when taking these medications. Clients using mifepristone for early pregnancy termination must call the health care provider if excessive bleeding occurs.
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