What is responsible for the high processivity of the Pol III holoenzyme?

A. The dNTP loader complex ensures continuous replication.
B. Because it has three polymerase cores, it can replicate three times as much DNA.
C. The hand-shaped structure of the polymerase core grasps the template DNA.
D. The ? sliding clamp allows Pol III to stay associated with the DNA template as each nucleotide is added.
E. The "thumb" structure of the Pol III polymerase core holds the DNA template tightly.


D

Biology & Microbiology

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