The nurse knows that a patient with a mood disorder who is exhibiting slurred speech and muscle weakness has likely developed which condition?

1. Lithium toxicity
2. Steven-Johnson syndrome
3. Aplastic anemia
4. QT interval prolongation


Answer: 1
Explanation: Lithium is the gold standard for treatment of bipolar disorder, but has a narrow therapeutic index; the ratio between the toxic dose and the therapeutic dose is low, thus increasing the risk for toxicity and side effects such as ataxia, slurred speech, and muscle weakness. Steven-Johnson syndrome is a serious dermatologic reaction that is associated with use of Lamotrigine. Aplastic anemia is associated with carbamazepine use, and QT interval prolongation can occur with the use of atypical antipsychotics.

Nursing

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