Takayasu's disease was diagnosed in a 34-year-old Japanese woman who had chronic progressive ischemia of her arms and hands
It was histologically characterized by infiltrates of macrophages and giant cells in the vessel wall and preferentially involved the
A. aorta
B. coronary arteries
C. femoral arteries
D. muscular arteries of the kidney
E. arterioles of the kidney
A
Takayasu's giant cell arteritis typically involves the aorta and its major branches. Narrowing of the orifices of the major arteries originating from the arch of the aorta causes ischemia of the upper extremities ("pulseless disease").
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