Dosage compensation in mammals typically involves the random inactivation of one of the two X chromosomes relatively early in development. Such X chromosome inactivation often leads to phenotypic mosaicism. Assume that black fur in cats is due to the
X-linked recessive gene b, whereas its dominant allele B produces yellow fur. A Bb heterozygote is a mosaic called "tortoise shell" or "calico." A mating between a black male and a calico female occurred. Give the phenotypes of the offspring.
A) all black regardless of sex
B) calico females, black females, yellow makes, and black males
C) calico females and yellow males
D) all calico regardless of sex
E) calico females, yellow females, black males, and yellow males
Answer: B
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