Was their hypothesis supported by this experiment and why?
Bartel and Szostak hypothesized that among a large pool of RNA molecules, some of them may contain the enzymatic ability to catalyze a covalent bond between nucleotides; these can be selected for in the laboratory. The chart above shows the results from their experiment. The x-axis shows the original pool and 10 pools that were derived from their tagging of RNA with specific enzymatic functions; the y-axis shows the rate of phosphoester (covalent) bond formation.
A. Yes, because pools 1 to 10 show a continual increase in covalent bond formation.
B. Yes, there is a definite increase from the original pool to the second pool, but not from pool 8-10.
C. No, because there is only a slight increase from the original pool to the first experimental pool.
D. No, because this figure does not give sufficient data to make that assumption.
A. Yes, because pools 1 to 10 show a continual increase in covalent bond formation.
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