Research has provided support for the theory that epigenetic modifications can result from defi-cient in utero nutrition causing which chronic disease? (select all that apply)

a. Obesity
b. Asthma
c. Cardiovascular disease
d. Diabetes
e. Crohn's disease


ANS: A, C, D
When researchers sought to investigate how exposure to famine in utero had impacted individu-als born in a historically prosperous country whose nutritional intake was dramatically impacted by WWII, they found that individuals who suffered nutritional deprivation in utero were more likely to suffer from obesity and diabetes as adults than individuals who had not experienced nutritional deprivation during gestation. Other data sets reveal elevated risk of cardiovascular and metabolic disease for offspring of individuals exposed during early development to fluctua-tions in agricultural yields. The research does support the development of asthma or Crohn's dis-ease.

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