To prevent yellow or brown discoloration of teeth in children, tetracyclines should not be given:
a. to children once the permanent teeth have developed.
b. to patients taking calcium supplements.
c. to pregnant patients after the fourth month of gestation.
d. with dairy products or antacids.
ANS: C
Tetracyclines bind to calcium in developing teeth, resulting in yellow or brown discoloration. They should not be given to pregnant women after the fourth month of gestation, because they will cause staining of deciduous teeth in the fetus. In children, discoloration occurs when tetracyclines are given between the ages of 4 and 8 years, because this is when permanent teeth are developing. Tetracycline binds with calcium, so absorption is diminished when the drug is given with calcium supplements, dairy products, or calcium-containing antacids; however, this does not affect tooth development.
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ANS:
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