Different modification of the histone have different effects on gene expression. For instance, the ninth amino acid of histone 3 is a lysine (H3K9 ) can be acetylated once or methylated up to three times. Which of the following is true regarding H3K9

modification?

A) If H3K9 is acetylated, then the gene will be repressed.
B) If H3K9 has a single methyl group, then the gene will be repressed.
C) If H3K9 has two methyl groups, then the gene will be activated.
D) If H3K9 has three methyl groups, it is maximally activated compared to only having one methyl group.
E) If H3K9 has three methyl groups, then the gene will be repressed.


Answer: E

Biology & Microbiology

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