In a child with acute lymphocytic leukemia (ALL), which manifestations are due to thrombocytopenia?
A) Weakness and fatigue
B) Bleeding and bruising
C) Fever and enlarged lymph nodes
D) Bone pain and limping
B) Bleeding and bruising
Explanation: A) Infection related to neutropenia, weakness and fatigue related to anemia, and bleeding related to thrombocytopenia may be clinically evident on diagnosis in children. Children with ALL may present with additional signs and symptoms that are consistent with site-specific organ infiltration of leukemic cells, such as bone pain and enlarged lymph nodes.
B) Infection related to neutropenia, weakness and fatigue related to anemia, and bleeding related to thrombocytopenia may be clinically evident on diagnosis in children. Children with ALL may present with additional signs and symptoms that are consistent with site-specific organ infiltration of leukemic cells, such as bone pain and enlarged lymph nodes.
C) Infection related to neutropenia, weakness and fatigue related to anemia, and bleeding related to thrombocytopenia may be clinically evident on diagnosis in children. Children with ALL may present with additional signs and symptoms that are consistent with site-specific organ infiltration of leukemic cells, such as bone pain and enlarged lymph nodes.
D) Infection related to neutropenia, weakness and fatigue related to anemia, and bleeding related to thrombocytopenia may be clinically evident on diagnosis in children. Children with ALL may present with additional signs and symptoms that are consistent with site-specific organ infiltration of leukemic cells, such as bone pain and enlarged lymph nodes.
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