Which of the following statements is evidence that supports the programmed theory of aging?
A) The life spans attained by parents and their offspring are negatively correlated.
B) Mutations perpetuate themselves through each cycle of cell division.
C) In cultures, cells go through a finite number of cell divisions before dying.
D) In cultures, cells from older donors divide faster than those from younger donors.
C
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Studies of in vitro cell proliferation have demonstrated that various species have a finite number of cell divisions. Life spans of parents and offspring are positively correlated. Mutation perpetration is a tenet of the error theory, not the programmed theory, of aging. Although longer life spans correlate positively with numbers of cell divisions in vitro, the rate of cell division is not affected.
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