A patient taking antipsychotic medication for schizophrenia is admitted with a temperature of 106° F. The admitting diagnosis is neuroleptic malignant syndrome resulting from antipsychotic medication
Which drug is indicated in treatment of this condition?
a. Edrophonium (Tensilon)
b. Dantrolene (Dantrium)
c. Baclofen (Lioresal)
d. Metaxalone (Skelaxin)
ANS: B
Dantrolene, a direct-acting skeletal muscle relaxant, is used to treat neuroleptic malignant syndrome associated with the use of antipsychotic agents. Edrophonium is an antidote for neuromuscular-blocking agents. Baclofen is a skeletal muscle relaxant used for the treatment of muscle spasticity resulting from multiple sclerosis (MS) and cerebral palsy. Metaxalone is used for muscle spasms.
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