Significant loss of blood volume causes an increase in which of the following? 1. Vascular tone 2. Secretion of antidiuretic hormone (ADH) 3. Heart rate
a. 1, 2, and 3
b. 2 and 3 only
c. 1 and 3 only
d. 1 and 2 only
ANS: A
As the blood loss becomes more severe (20%), atrial receptor activity decreases further. This in-creases the intensity of sympathetic discharge from the cardiovascular centers. Plasma ADH and heart rate continue to climb, as does peripheral vasculature tone.
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