What are some of the drug types whose primary action is to target the transporters in the presynaptic portion on the neuronal cell? Select all that apply

1. Opioid receptor agonists
2. Serotonin-reuptake inhibitors
3. Norepinephrine-reuptake inhibitors
4. Selective serotonin-reuptake inhibitors
5. Norepinephrine-dopamine-reuptake inhibitors.


Answer: 2, 3, 4, 5
Explanation: Some examples of drugs that target the transporters in the presynaptic portion on the neuronal cell, thereby making more neurotransmitter available for the receptors on the postsynaptic neuron, include selective serotonin-reuptake inhibitors, serotonin-reuptake inhibitors, norepinephrine-reuptake inhibitors, and norepinephrine- dopamine-reuptake inhibitors. Opioid agonists have chemical properties that mimic the body's own drug-to-receptor process and will produce the same response in the cell.

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