How are the epigenetic marks of a particular chromatin state preserved during cell division?

A. Parental, marked H2A-H2B dimers stay associated with strands after replication and recruit new H3-H4 tetramers.
B. H2A-H2B dimers and H3-H4 tetramers come off during replication and assemble with unmarked histones. These new octamers then rebind to the newly replicated DNA to form nucleosomes.
C. Parental, marked H3-H4 tetramers stay associated with strands after replication and recruit new H2A-H2B dimers.
D. Histone chaperones make sure that at least one component of each new nucleosome is marked.
E. None of these choices is correct.


B

Biology & Microbiology

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