In cancer cells one allele of the tumor suppressor gene p53 is frequently mutated so that the protein is inactive, not produced, or deleted
The other allele will usually have a normal sequence and the promoter remains intact but the gene is not expressed. Sequencing with sodium bisulfite modification of DNA can be used to detect which cytosines are methylated. If the cancer cell DNA is sequenced what would be the anticipated results?
A. Cytosines in or near the promoter region will be methylated
B. Cytosines in or near the promoter will not be methylated
C. Cytosines in the coding region will have an increased mehtylation
D. There will be no differences in the methylation pattern of the promoter of p53 from a cancer cell and a normal cell
A
You might also like to view...
What would the result be if a drug that blocks the action of polymerase was introduced into a virus-infected organism?
A) The virus would not be able to enter new host cells. B) The viral proteins would not be made and the virus would not be able to reproduce. C) The newly formed virions (virus particles) would be unable to leave the host cell. D) Viral proteins and viral DNA particles would not be able to be assembled.
The typical waking and sleeping cycles of most people can be described as:
a. crepuscular. b. nocturnal. c. diurnal. d. lunar. e. annual.
Vines in tropical rain forests must grow toward large trees before being able to grow toward the sun. To reach a large tree, the most useful kind of growth movement for a tropical vine presumably would be _____
A) negative thigmotropism B) negative phototropism C) negative gravitropism D) the opposite of circadian rhythms
Pickling is an effective means of food preservation involving
A) increasing oxygen content. B) increasing salt concentration. C) reducing pH. D) reducing oxygen content. E) increasing salt concentration or reducing pH or both.