Which patients would be candidates for the use of dronabinol [Marinol] to treat nausea and vomiting? (Select all that apply.)
a. A patient with a history of a psychiatric disorder
b. A patient with acquired immunodeficien-cy syndrome (AIDS)–induced anorexia
c. A patient with chemotherapy-induced nausea and vomiting
d. A patient with nausea who has used mari-juana in the past
e. A patient with postoperative nausea and vomiting
B, C, D
Two cannabinoids have been approved for medical use in the United States for AIDS-induced anorexia and CINV. Because these drugs do not produce the same "high" that smoking marijua-na does, their use is not contraindicated in patients who have used marijuana in the past. They do cause potentially unpleasant effects, such as temporal disintegration, dissociation, depersonaliza-tion, and dysphoria, so they are contraindicated in patients with psychiatric disorders. They are not approved for postoperative nausea and vomiting.
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