Why have scientists been unable to grow the majority of bacteria and archaea in pure culture in a laboratory setting?

A. Most microorganisms reside in extreme
environments that are toxic to human life, so
samples cannot be collected for cultivation of
the microbial inhabitants in the laboratory.
B. Many species have metabolic
requirements that are difficult to fulfill in the
laboratory.
C. DNA sequencing technology was not
sufficiently advanced to give scientists the
ability to identify prokaryotic species in
nature, a requisite for growing microbes in the
laboratory.
D. Cells with unusual morphological
characteristics cannot be grown in the
laboratory.


B

Biology & Microbiology

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