What property of the mucosal immune system enables breast milk to contain antibodies against microorganisms encountered in the gut or other mucosal tissues? Explain your answer
What will be an ideal response?
In nursing mothers, B cells activated in the gut or other mucosal tissue can home to the lactating mammary gland and secrete their dimeric IgA antibodies into the breast milk. This is due to a general property of the mucosal immune system in that lymphocytes activated in a mucosal tissue carry the integrin ?4:?7 that binds to the vascular addressin MAdCAM-1, which is expressed on the walls of blood vessels serving different types of mucosal tissue. Thus lymphocytes activated in one mucosal tissue can recirculate to another one as well as to the tissue in which they were activated.
You might also like to view...
attention-deficit disorder : Neurological disorder characterized by short span and poor concentration
Fill in the missing word in the definition for the key term.
Factors contributing to the development of acne vulgaris include:
A) endocrine disorders. B) heredity. C) food allergies. D) all of the above.
Identify Newton's law of acceleration.
A. A body in motion tends to remain in motion at the same speed in a straight line unless acted on by a force. B. For every action there is an opposite and equal reaction. C. A change in the acceleration of a body occurs in the same direction as the force that caused it. D. None of the answers is correct.
If an infection stays in a certain part of the body, it is:
A. recurrent. B. malignant. C. degenerate. D. systemic. E. localized.