Which of the following statements regarding myosin in skeletal muscle is TRUE?
A. Myosin cross-bridge heads contain two binding sites, one for actin and one for tropomyosin.
B. Myosin is an ATPase.
C. The rate of ATP hydrolysis by myosin is the same in all types of skeletal muscle.
D. All of the myosin cross-bridge heads in a thick filament are oriented and rotate in the same direction.
E. Troponin covers the binding site on myosin molecules until Ca2+ binds to troponin to remove it from its blocking position.
B
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