When educating a client with possible glucocorticoid dysfunction, the nurse will explain that the CRH controls the release of ACTH. The best time to perform the blood test to measure peak ACTH levels would be:
A) 06:00 to 08:00 AM
B) 10:00 to 12:00 AM
C) 04:00 to 6:00 PM
D) 09:00 to 11:00 PM
Ans: A
Feedback:
Levels of cortisol increase as ACTH levels rise and decrease as ACTH levels fall. There is considerable diurnal variation in ACTH levels, which reach their peak in the early morning (around 6 to 8 AM) and decline as the day progresses.
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