What statement related to clinical trials developed for pediatric cancers is most accurate?
a. Are accessible only in major pediatric centers
b. Do not require consent for standard therapy
c. Provide the best available therapy compared with an expected improvement
d. Are standardized to provide the same treatment to all children with the disease
ANS: C
Most clinical trials have a control group in which the patients receive the best available therapy currently known. The experimental group(s) receives treatment that is thought to be even better. The protocol outlines the therapy plan. Protocols are developed for many pediatric cancers. They can be accessed by pediatric oncologists throughout the United States. Consent is always required in treatment of children, especially for research protocols. The protocol is designed to optimize therapy for children based on disease type and stage.
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