A cocktail of 30 compounds was identified to harbor a corepressor, and subsequent separation and purification was performed to test individual compounds

Describe an experiment that would enable you to identify the specific compound that acts as a corepressor for a catabolic pathway. Be certain to explain what will be measured and how you could conclude which compound is a corepressor.
What will be an ideal response?


Answer: Experimental designs will vary, especially in whether transcripts, proteins, or enzyme function is quantified, all of which would enable measuring activity of the repressor. In all cases, a compound added to the system which shows significantly lower (basal) activity would indicate it is a corepressor. Compounds that do not act as a corepressor would result in no change in activity, meaning transcripts, proteins, and enzyme function would still be observed.

Biology & Microbiology

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Four-year old Sammy is having a temper-tantrum. In a final attempt to get his way, he yells to his mom, “I'm gonna hold my breath ‘til I die!” What is the primary reason that Sammy’s mom is unconcerned by this statement?  

A.  It is impossible for Sammy to control the contraction of his diaphragm and intercostal muscles since they are made up of smooth muscle. B.  As Sammy holds his breath, the decreasing levels of oxygen in his blood will lead to stimulation of the respiratory control center in his brain. C.  Sammy is too young to hold his breath for more than 30 seconds. D.  As Sammy holds his breath, the increasing levels of carbon dioxide in his blood will lead to stimulation of the respiratory control center in his brain. Clarify Question   What is the key concept addressed by the question? What type of thinking is required? Gather Content What do you already know about respiration? What other information is related to the question?   Choose Answer Given what you now know, what information is most likely to produce the correct answer?   Reflect on Process Did your problem-solving process lead you to the correct answer? If not, where did the process break down or lead you astray? How can you revise your approach to produce a more desirable result?

Biology & Microbiology

A change in the rate or frequency of movements in response to environmental stimuli is called taxis

Indicate whether the statement is true or false.

Biology & Microbiology

In contrast to eyes, the eyespots of most invertebrates

cannot a. detect light. b. distinguish darkness from daylight. c. form distinct images. d. discern shadows. e. possess photoreceptors.

Biology & Microbiology

Which of the following is not a characteristic of an endotoxin?

A. Neurotoxic B. Heat stable C. Moderate toxicity D. Weakly immunogenic

Biology & Microbiology