The nurse is providing education to a patient who has been prescribed both an antacid and ranitidine (Zantac). Which instruction should the nurse give the patient about taking the medica-tions?
a. "Take the antacid 1 hour after the ranitidine."
b. "The antacid and ranitidine should be taken at the same time for better effect."
c. "Take the antacid 15 minutes before the ranitidine."
d. "Take the antacid 30 minutes after the ranitidine."
A
Because antacids raise gastric pH, they can affect the dissolution and absorption of ranitidine. Therefore, 1 hour should separate administration of antacids and ranitidine.
Antacids and ranitidine should not be taken at the same time, because dissolution and absorption of ranitidine will be reduced.
One hour should separate administration of antacids and ranitidine. These intervals are not enough separation for the drugs.
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