The patient, a physician returning from a trip to the tropics, is prescribed chloroquine and asks the nurse how it works. What is the nurse's best response?

A) Blocks the plasmodium's ability to synthesize ribonucleic acid
B) Changes the metabolic pathways necessary for the reproduction of the plasmodium
C) Interrupts the cell wall preventing entry of nutrients into the plasmodium
D) It is alkaline and decreases the ability of the parasite to synthesize deoxyribonucleic acid (DNA).


B
Feedback:
Chloroquine is currently the mainstay of antimalarial therapy. This drug enters human red blood cells and changes the metabolic pathways necessary for the reproduction of the plasmodium (see Figure 12.1). In addition, this agent is directly toxic to parasites that absorb it, it is acidic, and it decreases the ability of the parasite to synthesize DNA, leading to a blockage of reproduction.

Nursing

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