Contraction of the fibrous or fibrovascular granulation tissue in a wound healing by secondary intention occurs as a result of the action of
A. angioblasts
B. myofibroblasts
C. macrophages
D. endothelial cells
E. vascular smooth muscle cells
B
Myofibroblasts have hybrid features of fibroblasts and smooth muscle cells. Like fibroblasts they can synthesize collagen, and like smooth muscle cells they can contract. Contraction of myofibroblasts can reduce the surface area of an open wound to 10% of its original size and is most evident in wounds healing by secondary intention.
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