Rituximab, used in the treatment of rheumatoid arthritis, depletes _____ through a process involving the cross-linking of _____ on the surface of NK cells and the induction of antibody-dependent cell-mediated cytotoxicity

a. NK cells; NKG2D
b. T cells: NKG2D
c. inflammatory cytokines; TNF-alpha
d. C-reactive protein; Fc?RIII
e. B cells; Fc?RIII.


e

Health & Biomechanics

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Mental health is the condition of being sound _____

A) emotionally and mentally B) emotionally and physically C) emotionally, mentally, and physically D) mentally and physically

Health & Biomechanics

Christiana Carter had no obvious problems until she was 18 months old, when she stopped gaining weight, her appetite became poor, and she had recurrent episodes of diarrhea

At 24 months, Christiana developed a cough with pulmonary infiltrates unresponsive to treatment with the antibiotics clarithromycin and trimethoprim/sulfamethoxazole. Within 3 months, she developed lymphadenopathy, hepatosplenomegaly, and fevers. A computed tomography scan revealed enlarged mesenteric and para-aortic lymph nodes. A biopsy of an enlarged axillary lymph node revealed acid-fast bacilli, and cultures from the lymph node and blood grew Mycobacterium fortuitum. HIV was ruled out after negative tests by ELISA and PCR. Serologic testing for tetanus antitoxoid antibody showed a normal post-vaccination level. Christiana's peripheral blood mononuclear cells (PBMCs) were cultured with interferon-? plus lipopolysaccharide with no significant increase in TNF-? production. A variety of broad-spectrum and anti-mycobacterial antibiotics were administered, lowering the fever, and over the course of the next 2 months Christiana began to gain weight but continued to show signs of persistent infection. Which of the following is the most likely explanation for these clinical findings? a. leukocyte adhesion deficiency b. chronic granulomatous disease c. interferon-? receptor deficiency d. X-linked agammaglobulinemia e. severe combined immune deficiency.

Health & Biomechanics

What is another way of describing renal calculi?

A) pyelocalculus B) pyelolithiasis C) nephrolithiasis

Health & Biomechanics

The number-one goal of first aid care for victims with COPD is to:

A) enhance oxygenation. B) loosen restrictive clothing. C) increase circulation. D) provide CPR.

Health & Biomechanics