A 6-year-old child cuts his leg while playing outside. An inflammatory process begins the healing process by moving leukocytes and platelets through the endothelial lining of blood vessels
This process occurs because of which extracellular tissue component?
A)
Extracellular matrix
B)
Glycosaminoglycans
C)
Selectins
D)
Cadherins
Ans:
C
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Selectins are found on activated endothelial cells of blood vessels, on leukocytes, and on platelets. They, together with integrins and immunoglobulins, participate in leukocyte movement through the endothelial lining of blood vessels during inflammation. Cadherins link parts of the internal cytoskeleton (actin and catenins) with extracellular cadherins of an adjacent cell. Glycosaminoglycans are one of the components of the extracellular matrix.
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