Hormone replacement therapy (HRT) is used to treat symptoms of menopause. What are these clients at an increased risk for developing as a result of the HRT? (Select all that apply.)

Note: Credit will be given only if all correct choices and no incorrect choices are selected.

1. Endometrial cancer
2. Stroke
3. Venous thromboembolism
4. Breast cancer
5. Coronary artery disease


Correct Answer: 2, 3, 5

Rationale 1: Endometrial cancer is incorrect because endometrial cancer is not a risk if progesterone is added to HRT.
Rationale 2: The choice of HRT to treat menopausal symptoms is highly individualized, and women should be encouraged to discuss alternatives with their health care provider. Data suggest that patients might have an increased risk of coronary artery disease, stroke, and venous thromboembolism.
Rationale 3: The choice of HRT to treat menopausal symptoms is highly individualized, and women should be encouraged to discuss alternatives with their health care provider. Data suggest that patients might have an increased risk of coronary artery disease, stroke, and venous thromboembolism.
Rationale 4: Breast cancer is incorrect because there is some data that suggests HRT helps prevent some breast cancers.
Rationale 5: The choice of HRT to treat menopausal symptoms is highly individualized, and women should be encouraged to discuss alternatives with their health care provider. Data suggest that patients might have an increased risk of coronary artery disease, stroke, and venous thromboembolism.

Global Rationale: The choice of HRT to treat menopausal symptoms is highly individualized, and women should be encouraged to discuss alternatives with their health care provider. Data suggest that patients might have an increased risk of coronary artery disease, stroke, and venous thromboembolism. Endometrial cancer is incorrect because endometrial cancer is not a risk if progesterone is added to HRT. Breast cancer is incorrect because there is some data that suggests HRT helps prevent some breast cancers.

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