Which statement is accurate regarding the use of beta-adrenergic blockers for use in patients with heart failure?
1. Higher doses are used initially until optimal vital signs are achieved.
2. Dosage changes are done on a daily basis for the first 2 weeks.
3. This drug class does not have an effect on the bronchioles of the lungs.
4. They are generally used in combination with other heart-failure drugs.
Correct Answer: 4
Rationale: Beta-adrenergic blockers are rarely used to treat heart failure alone. They are commonly used in combination with ACE inhibitors. Initial doses are small, and are doubled every 2 weeks until the optimal dose is achieved. Beta-adrenergic blockers can be selective to beta1 receptors or non-selective. Non-selective blockers block beta1 and beta2 receptors. The blockage of beta2 receptors can affect the bronchioles of the lungs.
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