What effect will occur if a patient being treated with naltrexone (ReVia) for substance abuse ingests opioids or alcohol?
a. Increased euphoria
b. Nausea, vomiting, and diarrhea
c. Deep sedation
d. An absence of the "high" associated with drugs
ANS: D
Naltrexone is an opioid antagonist prescribed to block the pharmacologic effects of the "high" associated with opioids and alcohol. Studies report less alcohol craving and fewer drinking days, especially when naltrexone is combined with psychosocial treatment. Naltrexone prevents the euphoria associated with taking drugs like opioids and alcohol. These are symptoms of taking alcohol in combination with disulfiram (Antabuse). Naltrexone is not sedating.
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