The Encyclopedia of DNA Elements (ENCODE) project aims to discover functional elements in DNA. One technique employed is DNase-seq. This technique employs a DNase enzyme that digests accessible regions of chromatin, while inaccessible regions remain undigested. The undigested DNA is then sequenced. Which of the following is likely true of the DNase-seq results?
A. The sequenced DNA will be the same from cell type to cell type.
B. Centromeric DNA is likely to be sequenced in all samples.
C. Unsequenced DNA is likely part of euchromatin.
D. Unsequenced DNA regions were likely bound to nucleosomes.
Ans:
B. Centromeric DNA is likely to be sequenced in all samples.
C. Unsequenced DNA is likely part of euchromatin.
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