A severely depressed patient has been prescribed clomipramine (Anafranil). For which medication side effects should the patient be monitored?
a. Excess salivation and drooling
b. Muscle rigidity and restlessness
c. Polyuria and coarse hand tremors
d. Orthostatic hypotension and constipation
ANS: D
Alpha1 blockade produces orthostatic hypotension, and cholinergic blockade produces con-stipation. Mild tremors and urinary retention may occur. Drooling and excessive salvation may occur with SSRIs. Muscle rigidity and restlessness may occur with antipsychotics.
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