A patient with PUD asks the nurse about the action of prokinetic medications. Which explanation by the nurse is accurate?
a. It blocks the formation of hydrochloric acid, reducing irritation of the gastric mucosa.
b. It increases the lower esophageal sphincter muscle pressure and peristalsis.
c. It reduces the secretion of saliva, hydrochloric acid, pepsin, bile, and other enzymatic fluids.
d. It decreases the volume of hydrochloric acid produced, increasing the gastric pH.
ANS: B
Prokinetic agents increase the lower esophageal sphincter muscle pressure and peristalsis, hastening emptying of the stomach to reduce reflux. Proton pump inhibitors block the formation of hydrochloric acid, reducing irritation of the gastric mucosa. Antispasmodic agents reduce the secretion of saliva, hydrochloric acid, pepsin, bile, and other enzymatic fluids necessary for digestion and decrease GI motility and secretions. H2 antagonists decrease the volume of hydrochloric acid produced, increasing the gastric pH, which results in decreased irritation to the gastric mucosa.
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