A patient with hypertension and poorly controlled diabetes complains of frequent urination. She does not take any medications yet for these conditions. What can explain her complaint?
A. Glomerular filtration rate decreases in response to excessive stretch of the glomerular capillaries in hypertension.
B. Blood glucose increases the osmotic pressure in the tubules, causing increased urine production.
C. Sympathetic stimulation increases when blood pressure increases, which causes dilation of the afferent arterioles.
D. Renal autoregulation prevents blood glucose from entering the filtrate, but the pressure in the glomerulus increases filtrate production.
Answer: B
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