Lung injury is more likely to occur with which of the following with normal lung tissue?
a. PA = 25 cm H2O; Ppl = 18 cm H2O
b. PA = 29 cm H2O; Ppl = 10 cm H2O
c. PA = 30 cm H2O; Ppl = 21 cm H2O
d. PA = 45 cm H2O; Ppl = 34 cm H2O
ANS: B
Situations in which the lung-distending pressure (i.e., transpulmonary pressure, or PA − Ppl) is abnormally high can cause lung injury. PA can be high by itself without causing lung damage, but if PA − Ppl is high, lung damage is more likely. The highest transpulmonary pressure is 19 cm H2O, when the PA = 29 cm H2O and the Ppl = 10 cm H2O.
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