A patient has a positive test for hepatitis C and is admitted to the hospital. The admission laboratory tests reveal a normal ALT, and a liver biopsy is negative for hepatic fibrosis and inflammation. The nurse will prepare this patient for:
a. dual therapy with pegylated interferon alfa and ribavirin.
b. no medication therapy at this time.
c. pegylated interferon alfa only until ALT levels are elevated.
d. triple drug therapy with pegylated interferon alfa, ribavirin, and boceprevir.
ANS: B
Current recommendations are that treatment is used only for patients with HCV viremia, persistent elevation of ALT, and evidence of hepatic fibrosis and inflammation upon liver biopsy. Dual therapy has been the regimen of choice for patients with the above symptoms, but the addition of a protease inhibitor has been shown to improve outcomes. It is not correct to give pegylated interferon alfa until ALT levels are elevated. Triple drug therapy is used for patients with the above symptoms.
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