A patient has begun taking dimethyl fumarate [Tecfidera] to treat relapsing MS and calls the clinic to report flushing of the skin with itching and burning sensations. What will the nurse recommend to this patient?
a. "Take a non–enteric-coated aspirin 30 minutes before each dose."
b. "The provider will order an antihistamine to treat this symptom."
c. "Try taking the medication on an empty stomach."
d. "You should notify the provider imme-diately."
A
The most common side effect of dimethyl fumarate is flushing, which decreases over time. Pa-tients should be counseled to take a non–enteric-coated aspirin 30 minutes prior to the dose and to take the medication with food. Antihistamines are not indicated. It is not a serious symptom and the provider does not need to be notified.
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