Which intervention is most important for the nurse to implement to prevent complications from tumor lysis syndrome during chemotherapy?

A. Ensure that the client has a fluid intake of 3000 to 5000 mL per day.
B. Monitor electrocardiograph rhythms every hour during therapy.
C. Apply pressure to all injection sites for 5 minutes.
D. Assist the client in all ambulatory activities.


A
Tumor lysis syndrome is the precipitation of intracellular products released when tumor cells are destroyed rapidly. These products, particularly purines, can increase uric acid crystal precipitation in the kidney tubules and cause acute tubular necrosis. In addition, serum potassium levels can become quite high. Maintaining adequate hydration and urine output is the key to preventing complications.

Nursing

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Traditional abstracts are single-paragraph summaries of the key features of a study

A) True B) False

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