What is the optimal PEEP level given the following information?

Time 0600 0615 0625 0635 0640 0650
PEEP 0 5 8 10 12 15
PaO2 (FIO2 = 0.6) 50 62 75 81 86 103
Cs (mL/cm H2O) 16 21 28 38 34 30
BP 140/90 130/90 120/90 120/90 118/80 100/70

a. 8 cm H2O
b. 10 cm H2O
c. 12 cm H2O
d. 15 cm H2O


ANS: B
At a PEEP of 10 cm H2O, the Cs is at its highest level, and the PaO2 and BP are at acceptable levels. At 12 cm H2O, the Cs is reduced, and it declines further at a PEEP of 15 cm H2O.

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