A 68-year-old male patient receives a prescription for 25-mg tablets of sildenafil [Viagra] for erectile dysfunction. When he asks the nurse how to take the medication, the nurse will tell him to:
a. begin taking one tablet twice daily, 12 hours apart.
b. start with one tablet about 1 hour before anticipated sexual activity.
c. take 25 to 100 mg per dose 30 minutes to 4 hours before sexual activity.
d. take two tablets 1 hour before sexual ac-tivity with a high-fat meal.
B
Patients older than 65 years should start with a low dose of 25 mg and may take the drug 1 hour before anticipated sexual activity. Sildenafil is taken when needed and not on a routine basis. Dosing at 25 to 100 mg per dose 30 minutes to 4 hours before sexual activity is the standard recommendation for men younger than 65 years. Two tablets is a high dose; consumption of a high-fat meal would interfere with absorption of sildenafil.
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