A patient is admitted to the local hospital with a pulmonary embolus. He was unconscious when admitted to the emergency department. Ultrasound revealed a large clot in the patient's saphenous vein
Thrombolytic therapy is administered, and eventually the patient's condition stabilizes. Laboratory tests are performed at hospital admission; their results follow:
PT: 15.5 sec
INR: 2.85
APTT: 76 sec
Protein C antigen: 14%
Protein C functional activity: 18%
Molecular studies: FV-R506Q present
Based on this information, what is the most probable diagnosis for this patient?
a. PC deficiency and factor V deficiency
b. PS deficiency and factor V deficiency
c. APCR and PC deficiency
d. HC-II deficiency
Correct Answer: C
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