In eukaryotic cells, the 5' cap is bound to a protein complex called cap binding complex. In addition, during the splicing reaction, proteins are deposited at sites where the exons are fused together. These proteins, in combination with the cap binding complex, are essential for the recruitment of an additional complex of proteins that is essential for mRNA export from the nucleus to the cytoplasm. This complex is called the transcription-export, or TREX, complex. Taking this into account, would an mRNA encoded by a virus infecting a eukaryotic cell need to bind to the TREX complex?
A. No, only eukaryotic mRNAs are modified, and therefore viral mRNAs do not need to bind to the TREX complex.
B. No, mRNAs encoded by viruses infecting eukaryotic cells can be translated in the nucleus of these cells.
C. Yes, mRNAs encoded by viruses infecting eukaryotic cells would need to bind these complexes to allow RNA processing events to occur.
D. Yes, mRNAs encoded by viruses infecting eukaryotic cells would still need to move from the nucleus to the cytoplasm to be translated.
Answer: D
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