An adolescent girl asks the school nurse for advice because she has dysmenorrhea. She says that a friend recommended she try an over-the-counter nonsteroidal anti-inflammatory drug (NSAID). The nurse's response should be based on what?
a. Hormone therapy is necessary for the treatment of dysmenorrhea.
b. Acetaminophen is the drug of choice for the treatment of dysmenorrhea.
c. Over-the-counter NSAIDs are rarely strong enough to provide adequate pain relief.
d. NSAIDs are effective because they inhibit prostaglandins, leading to reduction in uterine activity.
ANS: D
First-line therapy for adolescents with dysmenorrhea is NSAIDs. NSAIDs are potent anti-inflammatory agents that block the formation of prostaglandins, resulting in decreased uterine activity. Hormone therapy may be indicated if there is no physical abnormality and NSAIDs are ineffective. Acetaminophen does not have an antiprostaglandin action. It can help with pain control but will not be as effective as NSAIDs.
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